AmericanaPetLawn & GardenTruck & AutomotiveClothingPoultryHeating & CoolingHorseSporting GoodsOutdoor Power EquipmentFencing & GatesLivestockOutdoor LivingPet & Animal PharmacyToolsHome ImprovementFarm & RanchBoots & ShoesTrailers & TowingHome Decor & FurnitureWild Birds & WildlifeToysGift CardsServices Propane RefillTrailer RentalGarden CenterFeed CenterSame Day DeliveryPetVet ClinicPet WashGrooming at PetsenseDog Training at PetsenseTractor Supply RxPet InsuranceWag!

"Savings and Offers"

Weekly AdSaleClearance

"More Options"

Weekly AdWhat's NewTractor Supply AppEarn Rewards with Neighbor's ClubHometown HeroesLife Out Here BlogTSC Exclusive BrandsTop BrandsClearance ItemsBattery FinderOutdoor Power Equipment Parts FinderHitch Finder

All New Unbeatable Prices Have Arrived

|
Shop Now
Order statusTSC Credit CardsWhat’s newPetsenseWeekly Ad
​

Sign In / Enroll

Get rewarded!

A boy outside with a dog. A man is on one knee in the background.
A boy outside with a dog. A man is on one knee in the background.

Weed Killers

  1. Home

  2. /

  3. Farm & Ranch

  4. /

  5. Ag Chemicals

  6. /

  7. Weed Killers

{"store_id":2314,"page_number":1,"category":"Farm & Ranch>Ag Chemicals>Weed Killers","keywords":"weed-killers","item":"107445699,105561099,111059599,420154399,420101499,135237699,117081499,123229199,244888499,420151999,420384699,420102299,232266799,102109499,135445399,420116199,102849799,244888399,420553999,420159399,420111199,246809299,135035099,129209999,243528499,420108099,137836999,102400599,101214999,103008199,159859499,420563699,243528399,123820699,130563899,123820799,422111199,136415999,118422499,111715999,420173999,146421399,123820599,135033499,123168499,248529599,101422399,127132399","filters":[],"availability":"","price":"","id":""}
Pickup
Delivery

Smart Supply eligible

Auto order and save everyday

Sort by Most Popular
Pickup
Delivery

Weed Killers (93)

RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr
RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

4.6

(4037)

$159.99

$159

.99

Sale Was $179.99 Save $20.00

RM43 1 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr
RM43 1 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

RM43 1 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

4.6

(2643)

$109.99

$109

.99

Sale Was $119.99 Save $10.00

RM43 32 oz. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr
RM43 32 oz. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

RM43 32 oz. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

4.4

(342)

$49.99

$49

.99

Gordon's 2.5 gal. Amine 400 2 4-D Weed Killer
Gordon's 2.5 gal. Amine 400 2 4-D Weed Killer

Gordon's 2.5 gal. Amine 400 2 4-D Weed Killer

4.5

(471)

$79.99

$79

.99

Gordon's 1 gal. Amine 400 2 4-D Weed Killer
Gordon's 1 gal. Amine 400 2 4-D Weed Killer

Gordon's 1 gal. Amine 400 2 4-D Weed Killer

4.5

(113)

$34.99

$34

.99

Sale Was $44.99 Save $10.00

Compare-N-Save 64 oz. Weed Killer for Lawns, Concentrate
Compare-N-Save 64 oz. Weed Killer for Lawns, Concentrate

Compare-N-Save 64 oz. Weed Killer for Lawns, Concentrate

3.8

(34)

$14.99

$14

.99

Brushtox 32 oz. Brush Killer with Triclopyr, Concentrate
Brushtox 32 oz. Brush Killer with Triclopyr, Concentrate

Brushtox 32 oz. Brush Killer with Triclopyr, Concentrate

4.8

(78)

$36.99

$36

.99

Preen 31.3 lb. Garden Weed Preventer
Preen 31.3 lb. Garden Weed Preventer

Preen 31.3 lb. Garden Weed Preventer

4.7

(1471)

$42.99

$42

.99

Sale Was $54.99 Save $12.00

Gordon's Trimec Platinum All in One Weed Control Ready to Spray, 32 oz.
Gordon's Trimec Platinum All in One Weed Control Ready to Spray, 32 oz.

Gordon's Trimec Platinum All in One Weed Control Ready to Spray, 32 oz.

5.0

(1)

$29.99

$29

.99

Gordon's 1 gal. Trimec Lawn Weed Killer, Concentrate
Gordon's 1 gal. Trimec Lawn Weed Killer, Concentrate

Gordon's 1 gal. Trimec Lawn Weed Killer, Concentrate

4.2

(67)

$39.99

$39

.99

Sale Was $49.99 Save $10.00

Gordon's 2.5 gal. 15-0-0 Liquid Weed and Feed, Concentrate
Gordon's 2.5 gal. 15-0-0 Liquid Weed and Feed, Concentrate

Gordon's 2.5 gal. 15-0-0 Liquid Weed and Feed, Concentrate

4.6

(410)

$89.99

$89

.99

Gordon's 1 qt. Amine 400 2 4-D Weed Killer
Gordon's 1 qt. Amine 400 2 4-D Weed Killer

Gordon's 1 qt. Amine 400 2 4-D Weed Killer

4.3

(44)

$24.99

$24

.99

Roundup 1 gal. Dual Action 365 Weed and Grass Killer Plus, 12 Month Preventer with Comfort Wand
Roundup 1 gal. Dual Action 365 Weed and Grass Killer Plus, 12 Month Preventer with Comfort Wand

Roundup 1 gal. Dual Action 365 Weed and Grass Killer Plus, 12 Month Preventer with Comfort Wand

4.7

(103)

$49.99

$49

.99

Sale Was $59.99 Save $10.00

Gordon's 1 gal. Trimec Crabgrass Plus Lawn Weed Killer, Concentrate
Gordon's 1 gal. Trimec Crabgrass Plus Lawn Weed Killer, Concentrate

Gordon's 1 gal. Trimec Crabgrass Plus Lawn Weed Killer, Concentrate

3.9

(102)

$59.99

$59

.99

Sale Was $79.99 Save $20.00

Compare-N-Save 32 oz. Weed Killer for Lawns, Concentrate
Compare-N-Save 32 oz. Weed Killer for Lawns, Concentrate

Compare-N-Save 32 oz. Weed Killer for Lawns, Concentrate

3.2

(19)

$9.99

$9

.99

Roundup 2.5 gal. Powermax Weed Killer, Concentrate
Roundup 2.5 gal. Powermax Weed Killer, Concentrate

Roundup 2.5 gal. Powermax Weed Killer, Concentrate

4.7

(394)

$149.99

$149

.99

Currently Trending

  1. FarmWorks 2.5 gal. 41% Glyphosate Grass and Weed Killer Concentrate
    4.6 out of 5 stars with 4714 reviews
    4.6 (4714)

    FarmWorks 2.5 gal. 41% Glyphosate Grass and Weed Killer Concentrate

    $79.99
  2. Subscription Eligible
    RM43 1 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr
    4.6 out of 5 stars with 2643 reviews
    4.6 (2643)

    RM43 1 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

    $109.99
    Was $119.99Save $10.00
  3. RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr
    4.6 out of 5 stars with 4037 reviews
    4.6 (4037)

    RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

    $159.99
    Was $179.99Save $20.00
  4. Subscription Eligible
    Gordon's 2.5 gal. Amine 400 2 4-D Weed Killer
    4.5 out of 5 stars with 471 reviews
    4.5 (471)

    Gordon's 2.5 gal. Amine 400 2 4-D Weed Killer

    $79.99
  5. RM43 32 oz. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr
    4.4 out of 5 stars with 342 reviews
    4.4 (342)

    RM43 32 oz. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

    $49.99
  6. FarmWorks 1 gal. 53.8% Glyphosate Grass and Weed Killer Concentrate
    4.4 out of 5 stars with 465 reviews
    4.4 (465)

    FarmWorks 1 gal. 53.8% Glyphosate Grass and Weed Killer Concentrate

    $79.99
  7. RM43 64 oz. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr
    4.3 out of 5 stars with 194 reviews
    4.3 (194)

    RM43 64 oz. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

    $64.99
  8. FarmWorks 2.5 gal. FW 53.8% Glyphosate Grass and Weed Killer
    4.6 out of 5 stars with 859 reviews
    4.6 (859)

    FarmWorks 2.5 gal. FW 53.8% Glyphosate Grass and Weed Killer

    $129.99
    Was $149.99Save $20.00
  9. Compare-N-Save 1 gal. 41% Glyphosate Grass and Weed Killer Concentrate, Makes 85 gal.
    4.2 out of 5 stars with 516 reviews
    4.2 (516)

    Compare-N-Save 1 gal. 41% Glyphosate Grass and Weed Killer Concentrate, Makes 85 gal.

    $39.99
    Was $49.99Save $10.00
  10. Gordon's 2.5 gal. 15-0-0 Liquid Weed and Feed, Concentrate
    4.6 out of 5 stars with 410 reviews
    4.6 (410)

    Gordon's 2.5 gal. 15-0-0 Liquid Weed and Feed, Concentrate

    $89.99
  11. Tordon 1 qt. Ready-to-Use Lawn Herbicide
    4.7 out of 5 stars with 352 reviews
    4.7 (352)

    Tordon 1 qt. Ready-to-Use Lawn Herbicide

    $29.99
  • 1
  • 2

Compare

Add up to 4 items

Take Another Look

  1. FarmWorks 2.5 gal. 41% Glyphosate Grass and Weed Killer Concentrate
    4.6 out of 5 stars with 4714 reviews
    4.6 (4714)

    FarmWorks 2.5 gal. 41% Glyphosate Grass and Weed Killer Concentrate

    $79.99
  2. RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr
    4.6 out of 5 stars with 4037 reviews
    4.6 (4037)

    RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

    $159.99
    Was $179.99Save $20.00
  3. Subscription Eligible
    RM43 1 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr
    4.6 out of 5 stars with 2643 reviews
    4.6 (2643)

    RM43 1 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

    $109.99
    Was $119.99Save $10.00
  4. Subscription Eligible
    Gordon's 2.5 gal. Amine 400 2 4-D Weed Killer
    4.5 out of 5 stars with 471 reviews
    4.5 (471)

    Gordon's 2.5 gal. Amine 400 2 4-D Weed Killer

    $79.99
  5. Gordon's 2.5 gal. 15-0-0 Liquid Weed and Feed, Concentrate
    4.6 out of 5 stars with 410 reviews
    4.6 (410)

    Gordon's 2.5 gal. 15-0-0 Liquid Weed and Feed, Concentrate

    $89.99
  6. Gordon's 1 gal. Amine 400 2 4-D Weed Killer
    4.5 out of 5 stars with 113 reviews
    4.5 (113)

    Gordon's 1 gal. Amine 400 2 4-D Weed Killer

    $34.99
    Was $44.99Save $10.00
  7. Tordon 1 qt. Ready-to-Use Lawn Herbicide
    4.7 out of 5 stars with 352 reviews
    4.7 (352)

    Tordon 1 qt. Ready-to-Use Lawn Herbicide

    $29.99
  8. FarmWorks 2.5 gal. FW 53.8% Glyphosate Grass and Weed Killer
    4.6 out of 5 stars with 859 reviews
    4.6 (859)

    FarmWorks 2.5 gal. FW 53.8% Glyphosate Grass and Weed Killer

    $129.99
    Was $149.99Save $20.00
  9. Top Rated
    Brushtox 32 oz. Brush Killer with Triclopyr, Concentrate
    4.8 out of 5 stars with 78 reviews
    4.8 (78)

    Brushtox 32 oz. Brush Killer with Triclopyr, Concentrate

    $36.99
  10. GrazonNext 2 gal. HL Specialty Herbicide Concentrate
    4.7 out of 5 stars with 182 reviews
    4.7 (182)

    GrazonNext 2 gal. HL Specialty Herbicide Concentrate

    $159.99
  11. Subscription Eligible
    Remedy 1 gal. Herbicide, Concentrate
    4.7 out of 5 stars with 789 reviews
    4.7 (789)

    Remedy 1 gal. Herbicide, Concentrate

    $139.99
  12. Crossbow 1 gal. Herbicide Weed Killer Concentrate
    4.6 out of 5 stars with 181 reviews
    4.6 (181)

    Crossbow 1 gal. Herbicide Weed Killer Concentrate

    $89.99

May We Recommend

  1. Top Rated
    16 ft. x 50 in. Max 50 Feedlot 10-Line Galvanized Cattle Fence Panel
    4.8 out of 5 stars with 2471 reviews
    4.8 (2471)

    Unbranded16 ft. x 50 in. Max 50 Feedlot 10-Line Galvanized Cattle Fence Panel

    $37.99
  2. Fiskars Deluxe Stand-up Weeder (4-claw)
    3.6 out of 5 stars with 65 reviews
    3.6 (65)

    Fiskars Deluxe Stand-up Weeder (4-claw)

    $49.99
  3. Rubber Stall Mat
    4.6 out of 5 stars with 4931 reviews
    4.6 (4931)

    UnbrandedRubber Stall Mat

    $57.99
  4. Producer's Pride Guardian Chicken Coop, 14 Chicken Capacity
    4.2 out of 5 stars with 946 reviews
    4.2 (946)

    Producer's Pride Guardian Chicken Coop, 14 Chicken Capacity

    $499.99-$999.99
    Was $999.99Save up to $500.00
    Choose Options
  5. Subscription Eligible
    Tractor Supply Pelletized Bedding for Horses and Small Animals, 40 lb.
    4.8 out of 5 stars with 8944 reviews
    4.8 (8944)

    Tractor Supply Pelletized Bedding for Horses and Small Animals, 40 lb.

    $7.99
  6. Producer's Pride Defender Extra-Large Chicken Coop, 18 Chicken Capacity
    4.1 out of 5 stars with 1446 reviews
    4.1 (1446)

    Producer's Pride Defender Extra-Large Chicken Coop, 18 Chicken Capacity

    $1,299.99
  7. Top Rated
    6 ft. Studded T-Post, 1.25 lb. per ft. with Anchor Plate
    4.8 out of 5 stars with 1313 reviews
    4.8 (1313)

    Unbranded6 ft. Studded T-Post, 1.25 lb. per ft. with Anchor Plate

    $5.69
  8. Tractor Supply Flake Premium Pine Shavings, 8 cu. ft.
    4.7 out of 5 stars with 6457 reviews
    4.7 (6457)

    Tractor Supply Flake Premium Pine Shavings, 8 cu. ft.

    $5.99
  9. Top Rated
    Even Embers Tactical Propane Torch
    4.8 out of 5 stars with 6 reviews
    4.8 (6)

    Even Embers Tactical Propane Torch

    $99.99
  10. Winchester Safes 36 Long Gun 22.5 cu. ft. Electronic Lock Gun Safe, 45 Min. Fire Rating, Slate
    4.5 out of 5 stars with 3554 reviews
    4.5 (3554)

    Winchester Safes 36 Long Gun 22.5 cu. ft. Electronic Lock Gun Safe, 45 Min. Fire Rating, Slate

    $549.99
    Was $799.99Save $250.00
  11. Bad Boy Magnum 54 in., 24 hp Gas Zero-Turn Mower, Kohler Engine
    4.6 out of 5 stars with 231 reviews
    4.6 (231)

    Bad Boy Magnum 54 in., 24 hp Gas Zero-Turn Mower, Kohler Engine

    $3,999.99
  12. Coleman Powersports 196cc Gas Mini Bike, B200R
    4.2 out of 5 stars with 937 reviews
    4.2 (937)

    Coleman Powersports 196cc Gas Mini Bike, B200R

    $799.99

Related Categories

  • Dandelion Killers
  • Broadleaf Killers
  • Weed Control Fertilizers
  • Crabgrass Killers
  • Weed Control Granules
  • Organic Weed Killers For Pastures
  • Bug Killers
  • Lawn Insecticides
  • Weed And Lawn Care
  • Sprayers For Weeds
  • Season Long Weed Control
  • Lawn Pest Control Products
  • Ant Killers for Lawns
  • Weeding Accessories
  • Herbicide For Fence Lines
  • Lawn Care Spray
  • Trimmer Weeds
  • Natural Herbicides For Livestock Fields
  • Lawn Insect Killer Granules
  • Garden Weed Barriers

Related Articles

    Get the top deals, latest trends and more
    Sign up for emails from Tractor Supply today.
    First Name*
    Last Name*
    Email*

    Customer Support

    • Order Status

    • Return Policy

    • Delivery Options

    • Tax Exemptions

    • Frequently Asked Questions

    • Contact Us

    • Recall Notices

    • Call:  

      (877) 718-6750

    • Mon - Sat: 7am - 9pm CT

    • Sun: 8am - 7pm CT

    • Closed Christmas Day

    About Us

    • Who We Are

    • Investor Relations

    • Stewardship

    • Community

    • Military Support

    • Product Catalog

    • Tractor Supply Stores

    • .Pharmacy Verified Website

    Work With Us

    • Careers

    • Sponsorship

    • Affiliate Program

    • Potential Vendor Partners

    • Vendor Information

    • Tractor Supply Media Network

    Neighbor's Club

    • About

    • Rewards

    • Hometown Heroes

    • Frequently Asked Questions

    • Terms & Conditions

    Credit Center

    • TSC Credit Card

    • Klarna

    Stay Connected

    Connect & Share with the Tractor Supply Community.

    Tractor Supply App

    Shop on the go with the Tractor Supply App

    Learn More

    Stay Connected

    Connect & Share with the Tractor Supply Community.

    Tractor Supply App

    Shop on the go with the Tractor Supply App

    Learn More
    • Order Status

    • Return Policy

    • Delivery Options

    • Tax Exemptions

    • Frequently Asked Questions

    • Contact Us

    • Recall Notices

    • Call:  (877) 718-6750

    • Mon - Sat: 7am - 9pm CT

    • Sun: 8am - 7pm CT

    • Closed Christmas Day

    • Who We Are

    • Investor Relations

    • Stewardship

    • Community

    • Military Support

    • Product Catalog

    • Tractor Supply Stores

    • .Pharmacy Verified Website

    • Careers

    • Sponsorship

    • Affiliate Program

    • Potential Vendor Partners

    • Vendor Information

    • Tractor Supply Media Network

    • About

    • Rewards

    • Hometown Heroes

    • Frequently Asked Questions

    • Terms & Conditions

    • TSC Credit Card

    • Klarna

    Connect & Share with the Tractor Supply Community.

    Shop on the go with the Tractor Supply App

    Learn More
    • Privacy policy
    • Your Privacy Choices
    • Terms and Conditions
    • California Transparency Act
    • Legal Notices
    • Accessibility
    • Responsible Disclosure Statement
    • Surprise (Balance) Medical Billing Disclosure
    • Transparency in Coverage
    • Human Rights Policy
    • Vendor Code of Conduct
    • California Notice of Collection
    • Privacy Requests

    © 2026, Tractor Supply Co. All Rights Reserved.

    Sign in for a better experience

    Unlock deals, rewards & more.