RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr is ideal for fence rows, gravel paths, sidewalks, driveways, parking areas and around farm buildings and barns -- anywhere you want to spray once and be done for up to 1 year. This weed killer concentrate features a formula of glyphosate and imazapyr for effective use against most noxious weeds, grasses, vines, brush and trees. This weed prevention product is designed for use on non-crop areas as a spot treatment for brush, vines and weeds or on bare ground for total vegetation control. Do not spray this vegetation killer concentrate over the root systems of desirable plants. Get the beautiful looking yard you dream of with help from some RM43 vegetation control.

For additional information on this product, please see the Product Documents section for all downloadable user manuals, installation guides, brochures and warranty statements.

RM43 weed preventer treats 43,243 sq. ft.
This weed killer concentrate kills weeds and prevents weeds for up to 1 year
Ideal herbicide for fence rows, gravel paths, sidewalks, driveways, parking areas and around farm buildings and barns
Glyphosate and imazapyr formula for effective use against most noxious weeds, grasses, vines, brush and trees
Apply this weed prevention product to locations only where no vegetation is desired
This vegetation killer concentrate can be used for total vegetation control (bare ground) or spot control of brush, vines and weeds
Do not spray this vegetation killer concentrate over the root systems of desirable plants
Includes 2.5 gal. of herbicide
Use hand-operated spray equipment such as backpack sprayers, pump-up sprayers or sprinkling cans, or ATV/tractor-mounted sprayers to apply this weed killer

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Reviews

Rating Snapshot

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3189 reviews with 5 stars.

499 reviews with 4 stars.

156 reviews with 3 stars.

65 reviews with 2 stars.

123 reviews with 1 star.

Overall Rating

4.6

1138 out of 1245 (91%) reviewers recommend this product

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Summary of Reviews

AI-generated from customer reviews, which may include incentivized reviews.

This non-selective herbicide effectively kills a wide range of vegetation, including weeds, grass, and small trees and bushes. It takes 1-2 weeks to see full results, but the dead vegetation typically...

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Most Helpful Favorable Review

5 out of 5 stars.

one application

11 years ago

Forget all other weed killers. This kills everything and stays dead. Ihave tried the roundup and others but the weeds came right back. This is the real deal so it does cost more but it works best. Gets rid of weeds for good.

107 people found this helpful

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Most Helpful Critical Review

1 out of 5 stars.

price should be illegal

4 years ago

why has this product nearly doubled in price per the last 6 months? I will not buy this product until the price is lowered. Which I doubt will happen any time soon if at all.

16 people found this helpful

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Customer Images and Videos

effect on weeds
weeds
spraying
price
satisfaction
spraying
purchase
controlling

1 to 4 of 4032 Reviews .

1 – 4 of 4032 Reviews

Reviews 2

5 out of 5 stars.

Absolute vegetation killer/preventative!!!!

2 days ago

This product works amazingly. It takes about 2 weeks to see all the vegetation start to wither away. It killed everything including trees almost 2 inches thick. Would definitely refer to anyone looking for vegetation control or preventing vegetation from growing. All the people who left bad remarks or says it doesnt work clearly didn't mix it right is all! This item is like magic!!!!!!

Kennewick,WA

Review 1

4 out of 5 stars.

RM43 vegetation killer

16 days ago

This vegetation killer is fantastic!

SweepstakesYes

Yes, I recommend this product.

Tennessee

Review 1

5 out of 5 stars.

RM43 clearing

26 days ago

We've been using RM43 for more than 10 years now. We clear vegetation for cell towers. The only thing we complain about is not about the poison but that each tractor supply has different pricing for the product.

SweepstakesYes

Yes, I recommend this product.

East Tennessee

Review 1

1 out of 5 stars.

Do Not Buy, price gouging at it’s worst.

a month ago

RM43 2 1/2 gallon concentrate at tractor supply has increased from $109 last spring (2025) to $159 on sale now in spring 2026. Never again. This product claims to kill for up to a year but I have always needed at least 2 treatments in the growing season, Time to move on from this product to something more economical and reasonably priced. Suggest you do the same.

No, I do not recommend this product.

RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

RM43 2.5 gal. Total Vegetation Control Weed Preventer Concentrate with Glyphosate and Imazapyr

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Reviews

Rating Snapshot

Overall Rating

Review this Product

Thank you for your feedback

Most Helpful Favorable Review

one application

Most Helpful Critical Review

price should be illegal

Customer Images and Videos

Absolute vegetation killer/preventative!!!!

RM43 vegetation killer

RM43 clearing

Do Not Buy, price gouging at it’s worst.