Surpass (1% Diclofenac Sodium) Topical Anti-Inflammatory Cream for Horses is good for osteoarthritis in particular, this cream helps control pain and inflammation, enabling your horse to move better and feel better. The cream contains an NSAID called diclofenac and uses patented WISDOM technology to penetrate the horse's skin and slowly release the drug, offering lasting, targeted pain relief. For best results, apply Surpass joint pain cream to the affected area twice a day.How it Works

SURPASS® (1% diclofenac sodium) Topical Anti-Inflammatory Cream contains 1% diclofenac sodium contained in the WISDOM® Liposomal formulation. Diclofenac is a prescription non-narcotic, nonsteroidal anti-inflammatory drug (NSAID) used for the control of pain and inflammation associated with osteoarthritis (OA) in hock, knee, fetlock or pastern joints in horses.

Special Precautions

Exceeding the recommended dosage or treating multiple joints may increase plasma concentrations of diclofenac. The systemic effects of excess diclofenac doses that exceed the recommended label amount and duration have not been evaluated. As a class, NSAIDs may be associated with gastrointestinal and renal toxicity. When NSAIDs inhibit prostaglandins that cause inflammation, they may also inhibit prostaglandins that maintain normal homeostatic function. These anti-prostaglandin effects may result in clinically significant disease in patients with underlying or preexisting disease more often than in healthy patients. Patients at greatest risk for renal toxicity are those that are dehydrated, on concomitant diuretic therapy, or those with renal, cardiovascular and/or hepatic dysfunction. Horses should undergo a thorough history and physical examination before initiation of NSAID therapy. See product insert and packaging for full precautions.

Overdose Information

Immediately contact your closest emergency animal hospital or vet.

Side Effects

Adverse reactions associated with NSAIDs may include: weight loss, colic, diarrhea, or yellowing of the gums, skin, or whites of the eyes (jaundice). Serious adverse reactions associated with this drug class can occur without warning and, in rare situations, result in death. Discontinue the use of SURPASS® (1% diclofenac sodium) Topical Anti-Inflammatory Cream and contact your veterinarian immediately if these signs are observed. The majority of patients with drug-related reactions recover when the signs are recognized, drug administration is stopped, and veterinary care, if appropriate, is initiated. Adverse reactions during the safety study included a gastric ulcer in one horse that received 5.6x the recommended dosage, diarrhea and uterine discharge in one horse that received 2.8x the recommended dosage, and weight loss in four of the six horses in the 5.6x dosage group.

Storage

Store at up to 25°C (77°F). Protect from freezing.