Equioxx is an oral NSAID intended for use in horses only, anti-inflammatory, works to control pain and inflammation, helping your horse feel more comfortable and more mobile. A single dose of Equioxx offers pain relief for up to 24 hours. Equioxx comes in a tablet form and is FDA approved.How it Works

EQUIOXX® (firocoxib), a coxib class NSAID, targets COX-2 (cyclooxygenase-2), which is part of the chemical pathway resulting in pain and inflammation, while s/paring COX-1 (cyclooxygenase-1). It helps to maintain normal bodily functions, including blood flow to the kidneys and gastric mucosal protection.*1-4 *Clinical relevance has not been established. 1. Kvaternik V, Pollmeier M, et al, Pharmokinetics and metabolism of orally administered firocoxib, a novel second generation coxib in horses. J Vet Pharmacol Ther. 2007;30(3):208-217. 2. Data on file at Boehringer Ingelheim. Clinical Experience Report PHN 471, PR&D 0030701 3. Data on file at Boehringer Ingelheim, "Clinical Experience Report, PHN 471, Target Animal Safety Evaluation, Firocoxib (ML-1,785,713) Oral Paste for Horses." 4. Warner TD, Mitchell JA. Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum?. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13371-3.Insert #5

Special Precautions

Horses should undergo a thorough history and physical examination before initiation of NSAID therapy. Appropriate laboratory tests should be conducted to establish hematological and serum biochemical baseline data before and periodically during administration of any NSAID. Treatment with EQUIOXX® (firocoxib) should be terminated if signs such as inappetence, colic, abnormal feces, or lethargy are observed. See package insert for full information.

Overdose Information

Contact your closest emergency pet hospital.

Side Effects

The most common side effects associated with EQUIOXX® (firocoxib) therapy involve the tongue, lips and skin of the mouth and face (erosions and ulcers of the mucosa and skin) and the kidney. Gastrointestinal, kidney and liver problems have also been reported with other NSAIDs.

Storage

EQUIOXX® (firocoxib) Tablets: Store between 59-86°F (15-30°C) with brief excursions up to 104°F (40°C) permitted.