Skip to main content

Sign In / Enroll

Get rewarded!

4.6 out of 5 stars. 406 reviews
A woman outside with a dog
A woman outside with a dog

Frontline Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.

Frontline Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.

Item # 2427216

Pet Breed Size: 89 to 132 lb.

Months Supply: 3 Months

Neighbor's Club logo
Neighbor’s Club Members earn points with purchases.

Sign in or Join Now

Frontline Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.

Item # 2427216

Subscription options

$45.99

$45.99

Save $2.3 (5%)

Save 5% today and on all future orders

Conveniently pickup or deliver on a schedule you choose

No commitment – easily cancel anytime

$45.99

Pet Breed Size: 89 to 132 lb.

Months Supply: 3 Months

Shopping at

Grassland (franklin) TN

Delivery to

Spend $49 or more on Pet Food, Treats, Toys, Flea & Tick, and other select pet supplies and receive free standard delivery to home. Some exclusions ma...

Free standard delivery on online footwear & Clothing purchases of $49 and over.

Neighbor's Club logo
Neighbor’s Club Members earn points with purchases.

Sign in or Join Now

Protect your dog with FRONTLINE - the #1 name in flea and tick protection.* FRONTLINE Plus for Dogs provides fast-acting, long-lasting, flea and tick protection proven to kill adult fleas, flea eggs, flea larvae, chewing lice, and ticks. Trusted by pet owners for over 20 years,** one easy flea and tick topical application treatment works for 30 days.

Looking for more information on flea and tick control? Check out our flea and tick control buying guide in the product documents section.

  • Keep your dog protected from fleas & ticks all month long with FRONTLINE, the #1 name in flea and tick protection. FRONTLINE Plus for Dogs is a fast-acting, long-lasting flea & tick topical treatment thats proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
  • Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs, and flea larvae and prevent new infestations.
  • Trusted by pet owners for over 20 years, ** FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days.
  • FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5 lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products.
  • Treat the dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
  • Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus.

Q&As

1 - 6 of 6 Questions

Q: Does Frontline plus for dogs have the same ingredients as Frontline plus for cats

3 years ago
1 Answer
  • A: Active Ingredients for this product are: Fipronil 9.8% , (S)-methoprene 8.8%.
    3 years ago
    Helpful?

Q: Are there any harmful side effects of this medicine and if so what are they?

3 years ago
1 Answer
  • A: Hi countrygirlblues, For information on potential side effects please contact Frontline directly at For product information, report adverse events or any product related questions: call us 1 (888) 637-4251 (opt. 4)
    3 years ago
    Helpful?

Q: Can I use topical for 55lb dog on 15lb dog if I use less

4 years ago
1 Answer
  • A: No. This product is recommended for dogs who weigh 89 to 132 lb.
    4 years ago
    Helpful?

Q: My dog is 180 Lbs is it safe to use 2?

4 years ago
1 Answer
  • A: We advise consulting your veterinarian for the best recommendation as to your pet's specific needs.
    4 years ago
    Helpful?

Q: Is it water proof can I give my dog's a bath after using or if they go out when it's raining?

7 years ago
1 Answer
  • A: Yes, this is waterproof.
    7 years ago
    Helpful?

Q: What if it doesn't work? I used it and 5 days later, I'm still finding fleas!

8 years ago
1 Answer
  • A: We would advise you to consult your veterinarian whether or not you should continue use or switch to a different product.
    8 years ago
    Helpful?

Similar Items

  1. Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 3 ct.
    4.5 out of 5 stars with 461 reviews (461)

    Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 3 ct.

    $45.99
  2. Frontline Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.
    4.4 out of 5 stars with 542 reviews (542)

    Frontline Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.

    $45.99
  3. Frontline Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.
    4.6 out of 5 stars with 410 reviews (410)

    Frontline Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.

    $45.99
  4. Subscription Eligible
    PetArmor Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.
    4.3 out of 5 stars with 1234 reviews (1234)

    PetArmor Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.

    $27.99
    Was $31.99Save $4.00
  5. Top Rated
    Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 6-Month Supply, 6 ct.
    4.8 out of 5 stars with 317 reviews (317)

    Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 6-Month Supply, 6 ct.

    $74.98
  6. Frontline Plus Topical Flea, Tick and Lice Solution for Dogs
    4.3 out of 5 stars with 13 reviews (13)

    Frontline Plus Topical Flea, Tick and Lice Solution for Dogs

    $98.98-$149.96
  7. Top Rated
    Frontline Shield Flea and Tick Prevention for Dogs 11-20 lb., 3 ct.
    4.8 out of 5 stars with 922 reviews (922)

    Frontline Shield Flea and Tick Prevention for Dogs 11-20 lb., 3 ct.

    $52.48
  8. Top Rated
    Frontline Shield Flea and Tick Prevention for Dogs 21-40 lb., 3 ct.
    4.8 out of 5 stars with 922 reviews (922)

    Frontline Shield Flea and Tick Prevention for Dogs 21-40 lb., 3 ct.

    $52.48
  9. Top Rated
    Frontline Shield Flea and Tick Prevention for Dogs 41-80 lb., 3 ct.
    4.8 out of 5 stars with 923 reviews (923)

    Frontline Shield Flea and Tick Prevention for Dogs 41-80 lb., 3 ct.

    $58.99
  10. Top Rated
    Frontline Plus For Dogs Flea & Tick Spot Treatment X-Large Breed Dogs 89-132 lb., 6 ct.
    4.8 out of 5 stars with 320 reviews (320)

    Frontline Plus For Dogs Flea & Tick Spot Treatment X-Large Breed Dogs 89-132 lb., 6 ct.

    $74.98
  11. Top Rated
    Frontline Shield Flea and Tick Prevention for Dogs 81-120 lb., 3 ct.
    4.8 out of 5 stars with 925 reviews (925)

    Frontline Shield Flea and Tick Prevention for Dogs 81-120 lb., 3 ct.

    $52.48
  12. PetArmor Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.
    4.3 out of 5 stars with 1257 reviews (1257)

    PetArmor Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.

    $27.99
    Was $31.99Save $4.00

Items You May Like

  1. Subscription Eligible
    PetArmor Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.
    4.3 out of 5 stars with 1234 reviews (1234)

    PetArmor Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.

    $27.99
    Was $31.99Save $4.00
  2. Frontline Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.
    4.6 out of 5 stars with 410 reviews (410)

    Frontline Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.

    $45.99
  3. NextStar Flea and Tick Topical Treatment for X-Large Dogs, 3 Month Supply, 3 ct.
    4.3 out of 5 stars with 402 reviews (402)

    NextStar Flea and Tick Topical Treatment for X-Large Dogs, 3 Month Supply, 3 ct.

    $35.99
    Was $39.99Save $4.00
  4. Top Rated
    Frontline Plus For Dogs Flea & Tick Spot Treatment X-Large Breed Dogs 89-132 lb., 6 ct.
    4.8 out of 5 stars with 320 reviews (320)

    Frontline Plus For Dogs Flea & Tick Spot Treatment X-Large Breed Dogs 89-132 lb., 6 ct.

    $74.98
  5. Frontline Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.
    4.4 out of 5 stars with 542 reviews (542)

    Frontline Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.

    $45.99
  6. Top Rated
    Frontline Plus For Dogs Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lb., 6 ct.
    4.8 out of 5 stars with 329 reviews (329)

    Frontline Plus For Dogs Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lb., 6 ct.

    $74.98
  7. Top Rated
    Frontline Shield Flea and Tick Prevention for Dogs 81-120 lb., 3 ct.
    4.8 out of 5 stars with 925 reviews (925)

    Frontline Shield Flea and Tick Prevention for Dogs 81-120 lb., 3 ct.

    $52.48
  8. PetArmor Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.
    4.3 out of 5 stars with 1237 reviews (1237)

    PetArmor Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.

    $27.99
    Was $31.99Save $4.00
  9. PetArmor Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.
    4.3 out of 5 stars with 1257 reviews (1257)

    PetArmor Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.

    $27.99
    Was $31.99Save $4.00
  10. Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 3 ct.
    4.5 out of 5 stars with 461 reviews (461)

    Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 3 ct.

    $45.99
  11. Subscription Eligible
    NextStar Flea and Tick Topical Treatment for Large Dogs, 3 ct.
    4.2 out of 5 stars with 409 reviews (409)

    NextStar Flea and Tick Topical Treatment for Large Dogs, 3 ct.

    $35.99
    Was $39.99Save $4.00
  12. Top Rated
    Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 6-Month Supply, 6 ct.
    4.8 out of 5 stars with 317 reviews (317)

    Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 6-Month Supply, 6 ct.

    $74.98

Customers Also Bought

  1. Subscription Eligible
    Sulfodene 3-Way Wound Treatment Dog Ointment, 2 oz.
    4.7 out of 5 stars with 124 reviews (124)

    Sulfodene 3-Way Wound Treatment Dog Ointment, 2 oz.

    $12.99
  2. Frontline Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.
    4.4 out of 5 stars with 542 reviews (542)

    Frontline Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.

    $45.99
  3. Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 3 ct.
    4.5 out of 5 stars with 461 reviews (461)

    Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 3 ct.

    $45.99
  4. Frontline Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.
    4.6 out of 5 stars with 410 reviews (410)

    Frontline Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.

    $45.99
  5. Top Rated
    Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 6-Month Supply, 6 ct.
    4.8 out of 5 stars with 317 reviews (317)

    Frontline Plus Flea and Tick Topical Treatment for Dogs Up to 22 lb., 6-Month Supply, 6 ct.

    $74.98
  6. Top Rated
    Frontline Plus For Dogs Flea & Tick Spot Treatment X-Large Breed Dogs 89-132 lb., 6 ct.
    4.8 out of 5 stars with 320 reviews (320)

    Frontline Plus For Dogs Flea & Tick Spot Treatment X-Large Breed Dogs 89-132 lb., 6 ct.

    $74.98
  7. Subscription Eligible
    PetArmor Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.
    4.3 out of 5 stars with 1234 reviews (1234)

    PetArmor Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.

    $27.99
    Was $31.99Save $4.00
  8. Top Rated
    Frontline Plus For Dogs Flea & Tick Spot Treatment for Medium Breed Dogs 23-44 lb., 6 ct.
    4.8 out of 5 stars with 317 reviews (317)

    Frontline Plus For Dogs Flea & Tick Spot Treatment for Medium Breed Dogs 23-44 lb., 6 ct.

    $74.98
  9. Top Rated
    Frontline Plus For Dogs Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lb., 6 ct.
    4.8 out of 5 stars with 329 reviews (329)

    Frontline Plus For Dogs Flea & Tick Spot Treatment for Large Breed Dogs 45-88 lb., 6 ct.

    $74.98
  10. Frontline Plus Topical Flea, Tick and Lice Solution for Dogs
    4.3 out of 5 stars with 13 reviews (13)

    Frontline Plus Topical Flea, Tick and Lice Solution for Dogs

    $98.98-$149.96
  11. PetArmor Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.
    4.3 out of 5 stars with 1237 reviews (1237)

    PetArmor Plus Flea and Tick Topical Treatment for Dogs 23-44 lb., 3 ct.

    $27.99
    Was $31.99Save $4.00
  12. PetArmor Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.
    4.3 out of 5 stars with 1257 reviews (1257)

    PetArmor Plus Flea and Tick Topical Treatment for Dogs 45-88 lb., 3 ct.

    $27.99
    Was $31.99Save $4.00

Reviews

Rating Snapshot

Select a row below to filter reviews.
323 reviews with 5 stars.
40 reviews with 4 stars.
20 reviews with 3 stars.
5 reviews with 2 stars.
18 reviews with 1 star.

Overall Rating

4.6
323 out of 341 (95%) reviewers recommend this product

Review this Product

Select to rate the item with 1 star. This action will open submission form.
Select to rate the item with 2 stars. This action will open submission form.
Select to rate the item with 3 stars. This action will open submission form.
Select to rate the item with 4 stars. This action will open submission form.
Select to rate the item with 5 stars. This action will open submission form.
Adding a review will require a valid email for verification
  • for dogs
  • pest control
  • satisfaction
  • purchase
  • protection
  • ease of use
  • price
  • large
1 to 4 of 406 Reviews .
1 – 4 of 406 Reviews
Turlock ca
Review 1

Does not work

3 months ago
Does not work, applied to my dog as directed and fleas did not die.
SweepstakesYes

No, I do not recommend this product.

Valley Bend. WV
Reviews 13

Stops the itch

10 months ago
My dogs were itching until I put this on them
SweepstakesYes

Yes, I recommend this product.

WV
Review 1

Frontline Plus

10 months ago
Excellent product. No fleas or ticks in 10 plus years using Frontline Plus.
SweepstakesYes

Yes, I recommend this product.

Reviews 4

What’s changed with Frontline Plus??

11 months ago
I am so disappointed! I’ve used frontline plus for years. Just purchased 6/28/25. Bathed my dog extremely well, dried him and waited an additional hour to make sure he was dry just in case this affected how it worked. I applied as directed and as I have for years! Next day still has live fleas. It’s now 7/2/25 and he still has many live fleas! Has done nothing! I will be returning remaining 2 doses for an exchange of another brand in hopes my dog gets some relief! Highly disappointed in this brand!

No, I do not recommend this product.