Sentinel Spectrum is indicated for the prevention of heartworm disease, the prevention and control of flea populations, and the treatment and control of adult roundworm, hookworm, whipworm, and tapeworm infections in dogs and puppies weighing two pounds or more and six weeks of age or older. They also sterilize adult fleas and prevent eggs from hatching, which protects against future flea infestations.How it Works

One active ingredient of Sentinel Spectrum, milbemycin oxime:

• Is a macrocyclic anthelmintic, thought to work by impeding invertebrate neurotransmission
• Kills heartworm larvae in the tissue stage
• Eliminates hookworm (Ancylostoma caninum) in the adult stage
• Eradicates whipworm (Trichuris vulpis), roundworm (Toxocara canis and Toxascaris leonina), and hookworm (Ancylostoma caninum) infestations, as long as the medication is orally administered following the recommended dosage schedule.

• Safe use in puppies under 11 weeks old or in nursing or pregnant dogs has not been proven.
• A short-term shock-like reaction may occur if an adult heartworm-infected animal (therefore experiencing circulating microfilariae) is dosed with Sentinel Spectrum. To prevent this from occurring, an adult heartworm test should be performed before starting this medication. If the dog is found to have adult heartworms, they should be appropriately treated before starting on Sentinel Spectrum.

• Weakness
• Hypersalivation (drooling)
• Convulsions
• Ataxia (impaired coordination)
• Skin congestion
• Anorexia
• Diarrhea
• Urticaria (hives)
• Pruritus (itching)
• Lethargy
• Depression
• Vomiting