Skip to main content
FallHalloweenPetLawn & GardenTruck & AutomotiveClothingPoultryHeating & CoolingHorseSporting GoodsOutdoor Power EquipmentFencing & GatesLivestockOutdoor LivingPet & Animal PharmacyToolsHome ImprovementFarm & RanchBoots & ShoesTrailers & TowingHome Decor & FurnitureWild Birds & WildlifeToysGift CardsServices Propane RefillTrailer RentalGarden CenterFeed CenterSame Day DeliveryPetVet ClinicPet WashGrooming at PetsenseDog Training at PetsenseTractor Supply RxPet InsuranceWag!

"Savings and Offers"

Weekly AdSaleClearance

"More Options"

Weekly AdWhat's NewTractor Supply AppEarn Rewards with Neighbor's ClubHometown HeroesLife Out Here BlogTSC Exclusive BrandsTop BrandsClearance ItemsBattery FinderOutdoor Power Equipment Parts FinderHitch Finder

Limited time savings!

|
Shop Wild Steals Now
Order statusTSC Credit CardsWhat’s newPetsenseWeekly Ad
​

Sign In / Enroll

Get rewarded!

​
Menu

Search

Home

Sign In

Cart
4.7
(58)
4.7 out of 5 stars. 58 reviews
A woman outside with a dog
A woman outside with a dog
  1. Home
  2. /
  3. Pet
  4. /
  5. Cat
  6. /
  7. Cat Flea & Tick
  8. /
  9. Cat Topical Spot-on Flea & Tick Control
  10. /

  11. Advantage II Flea Prevention and Topical Treatment for Cats 5 lb. to 9 lb., 6 ct.

  1. Home
  2. /
  4. /
  5. Cat Topical Spot-on Flea & Tick Control

Advantage II Flea Prevention and Topical Treatment for Cats 5 lb. to 9 lb., 6 ct.

Shop all Advantage
Advantage II Flea Prevention and Topical Treatment for Cats 5 lb. to 9 lb., 6 ct.

Item # 1108747

Fulfilled by

allivetLogo

Advantage Advantage II Flea Prevention and Topical Treatment for Cats 5 lb. to 9 lb., 6 ct.
Advantage Advantage II Flea Prevention and Topical Treatment for Cats 5 lb. to 9 lb., 6 ct.

Save up to 40% on first Smart Supply

or up to 20% on one‑time purchase

Smart SupplyTM

Auto order & save every day

$74.99

Save 40% on your first Autoship order, up to $25.

Save 5%Save 5% on Autoship future orders.
ConvenientConvenient deliveries on a schedule you choose
FreeFree Standard Delivery on Rx orders over $30 & non-Rx orders over $49
No commitmentNo commitment easily cancel anytime
6 months
Order every

One Time Purchase

$74.99

Save 20%, up to $20

Pet Breed Size: 5 to 14 lb.

Months Supply: 6 Months

Notice:
  • This Item cannot be shipped to CA.
  • This item is non-returnable.
Neighbor's Club logo
Neighbor’s Club Members earn points with purchases.

Sign in or Join Now

Shop all Advantage
Advantage II Flea Prevention and Topical Treatment for Cats 5 lb. to 9 lb., 6 ct.

Item # 1108747

Fulfilled by

allivetLogo

Advantage Advantage II Flea Prevention and Topical Treatment for Cats 5 lb. to 9 lb., 6 ct.
Advantage Advantage II Flea Prevention and Topical Treatment for Cats 5 lb. to 9 lb., 6 ct.

Save up to 40% on first Smart Supply

or up to 20% on one‑time purchase

Smart SupplyTM

Auto order & save every day

$74.99

Save 40% on your first Autoship order, up to $25.

Save 5%Save 5% on Autoship future orders.
ConvenientConvenient deliveries on a schedule you choose
FreeFree Standard Delivery on Rx orders over $30 & non-Rx orders over $49
No commitmentNo commitment easily cancel anytime
6 months
Order every

One Time Purchase

$74.99

Save 20%, up to $20

Pet Breed Size: 5 to 14 lb.

Months Supply: 6 Months

​
Notice:
  • This Item cannot be shipped to CA.
  • This item is non-returnable.
Neighbor's Club logo
Neighbor’s Club Members earn points with purchases.

Sign in or Join Now

The Advantage II Flea Prevention and Topical Treatment for Cats 5 lb. to 9 lb. is a once-a-month topical flea prevention and treatment for cats. This flea control treatment kills lice of all ages within 12 hours of application. With a fragrance-free and waterproof formula, this cat flea treatment is long-lasting and will protect your feline from harmful, pesky pests. Keep your furry friend protected against biting, dangerous insects by regularly applying this Advantage II treatment.Note: This product may require up to 2 additional days for order processing prior to shipping

Looking for more information on flea and tick control? Check out our flea and tick control buying guide in the product documents section.

  • For use of flea control only on cats 8 weeks and older
  • Use the Advantage II treatment to kill all flea life stages
  • Controls existing flea infestations on your cat and prevents further infestations
  • Kills fleas within 12 hours of application
  • Convenient, easy-to-apply topical flea prevention solution for cats
  • Fragrance-free cat flea treatment for safe, effective use
  • Waterproof formula offers lasting protection
BrandAdvantage
Country of OriginMade in USA
Animal TypeCat
Breed SizeLarge, Small, Extra Large, Medium
Life StageAll Life Stages
Manufacturer BrandBayer
Recommended Pet Age8 weeks and older
Sold ByOther
Targeted InsectsFleas
Manufacturer Part NumberBAY-81520216

Frequently Bought Together

  1. Advantage II Flea Prevention and Topical Treatment for Cats 9 lb. and Up, 6 ct.
    4.7 out of 5 stars with 106 reviews
    4.7 (106)

    Advantage II Flea Prevention and Topical Treatment for Cats 9 lb. and Up, 6 ct.

    $74.99
  2. Advantage II Large Cat Vet-Recommended Flea Treatment and Prevention for Cats Over 9 lb., 4-Month Supply, 4 ct.
    4.6 out of 5 stars with 232 reviews
    4.6 (232)

    Advantage II Large Cat Vet-Recommended Flea Treatment and Prevention for Cats Over 9 lb., 4-Month Supply, 4 ct.

    $51.99
  3. Hill's Science Diet Kitten Savory Turkey Entree Wet Cat Food, 5.5 oz.
    4.4 out of 5 stars with 20 reviews
    4.4 (20)

    Hill's Science Diet Kitten Savory Turkey Entree Wet Cat Food, 5.5 oz.

    $2.59
    Choose Options
  4. Advantage II Topical Flea Prevention for Cats
    4.7 out of 5 stars with 48 reviews
    4.7 (48)

    Advantage II Topical Flea Prevention for Cats

    $19.99
    Choose Options
  5. Top Rated
    Delectables Bisque Variety Pack Lickable Cat Treat and Topper, 12 ct.
    4.9 out of 5 stars with 58 reviews
    4.9 (58)

    Delectables Bisque Variety Pack Lickable Cat Treat and Topper, 12 ct.

    $15.49
  6. Temptations Classic Savory Salmon Flavor Crunchy and Soft Treats For Cats, 48 oz. Tub
    4.7 out of 5 stars with 3069 reviews
    4.7 (3069)

    Temptations Classic Savory Salmon Flavor Crunchy and Soft Treats For Cats, 48 oz. Tub

    $24.99
  7. Hill's Science Diet Puppy Chicken and Barley Entree Wet Dog Food, 13 oz.
    4.6 out of 5 stars with 57 reviews
    4.6 (57)

    Hill's Science Diet Puppy Chicken and Barley Entree Wet Dog Food, 13 oz.

    $3.69
    Choose Options
  8. PetArmor Plus Topical Flea and Tick Control for Cats
    3.8 out of 5 stars with 429 reviews
    3.8 (429)

    PetArmor Plus Topical Flea and Tick Control for Cats

    $27.99-$42.27
    Was $31.99Save up to $4.00
    Choose Options
  9. Top Rated
    Purina Friskies Tasty Treasures Adult Fish-A-Licious in Sauce Wet Cat Food Variety Pack, 5.5 oz., Pack of 32 Cans
    4.8 out of 5 stars with 248 reviews
    4.8 (248)

    Purina Friskies Tasty Treasures Adult Fish-A-Licious in Sauce Wet Cat Food Variety Pack, 5.5 oz., Pack of 32 Cans

    $26.99
    Was $28.99Save $2.00
  10. Top Rated
    Purina Friskies Party Mix Beachside Whitefish Flavor Crunchy Adult Cat Treats, 20 oz.
    4.8 out of 5 stars with 459 reviews
    4.8 (459)

    Purina Friskies Party Mix Beachside Whitefish Flavor Crunchy Adult Cat Treats, 20 oz.

    $8.99
    Was $10.99Save $2.00
  11. Wondercide Ready to Use Flea, Tick, and Mosquito Yard Spray with Natural Essential Oils - 32 oz
    4.3 out of 5 stars with 316 reviews
    4.3 (316)

    Wondercide Ready to Use Flea, Tick, and Mosquito Yard Spray with Natural Essential Oils - 32 oz

    $39.99
  12. Purina Friskies Adult Surfin' and Turfin' Pate Favorites Wet Cat Food Variety Pack, 5.5 oz., Pack of 32 Cans
    4.7 out of 5 stars with 344 reviews
    4.7 (344)

    Purina Friskies Adult Surfin' and Turfin' Pate Favorites Wet Cat Food Variety Pack, 5.5 oz., Pack of 32 Cans

    $26.99
    Was $28.99Save $2.00

Reviews

Rating Snapshot

Select a row below to filter reviews.

5 starsstars

45
45 reviews with 5 stars.

4 starsstars

9
9 reviews with 4 stars.

3 starsstars

3
3 reviews with 3 stars.

2 starsstars

0
0 reviews with 2 stars.

1 starstars

1
1 review with 1 star.

Overall Rating

4.7
1 out of 2 (50%) reviewers recommend this product

Review this Product

Select to rate the item with 1 star. This action will open submission form.
Select to rate the item with 2 stars. This action will open submission form.
Select to rate the item with 3 stars. This action will open submission form.
Select to rate the item with 4 stars. This action will open submission form.
Select to rate the item with 5 stars. This action will open submission form.
Adding a review will require a valid email for verification
  • for cats
  • pest control
  • functional
  • satisfaction
  • smell
  • purchase
  • quality
  • reliable
1 to 4 of 58 Reviews .
1 – 4 of 58 Reviews
Sort by
Most Recent
NaomiM
Review 1
4 out of 5 stars.

Great treatment for cats

13 days ago
Advantage II keeps the bugs away. The scent was minimal and she didn’t have any issues with absorption on her skin. The quality was great and kept the bugs away.

Originally posted on elanco

TraciC
Review 1
5 out of 5 stars.

Fantastic monthly flea feline product!

20 days ago
I have had cats my entire life and worked in the. Veterinary field with access to a large variety of brands of cat & dog flea treatments… I really like the efficacy of the Advantage II products! Much better than any Frontline & Frontline Plus & Frontline Gold. It truly works well to control fleas on a monthly basis!

Originally posted on influenster.com

JeremyD
Review 1
5 out of 5 stars.

A simple to use product that performs exactly as described.

29 days ago
This product went on easily and my cat was not bothered at all by it. The product was just the right amount for my size cat. It was incredibly easy to use, and I did not have any problem with pests while using it.

Originally posted on elanco

IonelaC
Review 1
5 out of 5 stars.

It did the trick!

a month ago
The solution did the trick! My cat felt better after the first dosage and it was easy to apply by the neck! I stored the solution at room temperature with no issues.

Originally posted on influenster.com

Get the top deals, latest trends and more
Sign up for emails from Tractor Supply today.
First Name*
Last Name*
Email*

Customer Support

  • Order Status

  • Return Policy

  • Delivery Options

  • Tax Exemptions

  • Frequently Asked Questions

  • Contact Us

  • Recall Notices

  • Call:  

    (877) 718-6750

  • Mon - Sat: 7am - 9pm CT

  • Sun: 8am - 7pm CT

  • Closed Christmas Day

About Us

  • Who We Are

  • Investor Relations

  • Stewardship

  • Community

  • Military Support

  • Product Catalog

  • Tractor Supply Stores

  • .Pharmacy Verified Website

Work With Us

  • Careers

  • Sponsorship

  • Affiliate Program

  • Potential Vendor Partners

  • Vendor Information

  • Tractor Supply Media Network

Neighbor's Club

  • About

  • Rewards

  • Hometown Heroes

  • Frequently Asked Questions

  • Terms & Conditions

Credit Center

  • TSC Credit Card

  • Klarna

Stay Connected

Connect & Share with the Tractor Supply Community.

Tractor Supply App

Shop on the go with the Tractor Supply App

Learn More

Stay Connected

Connect & Share with the Tractor Supply Community.

Tractor Supply App

Shop on the go with the Tractor Supply App

Learn More
  • Order Status

  • Return Policy

  • Delivery Options

  • Tax Exemptions

  • Frequently Asked Questions

  • Contact Us

  • Recall Notices

  • Call:  (877) 718-6750

  • Mon - Sat: 7am - 9pm CT

  • Sun: 8am - 7pm CT

  • Closed Christmas Day

  • Who We Are

  • Investor Relations

  • Stewardship

  • Community

  • Military Support

  • Product Catalog

  • Tractor Supply Stores

  • .Pharmacy Verified Website

  • Careers

  • Sponsorship

  • Affiliate Program

  • Potential Vendor Partners

  • Vendor Information

  • Tractor Supply Media Network

  • About

  • Rewards

  • Hometown Heroes

  • Frequently Asked Questions

  • Terms & Conditions

  • TSC Credit Card

  • Klarna

Connect & Share with the Tractor Supply Community.

Shop on the go with the Tractor Supply App

Learn More
  • Privacy policy
  • Your Privacy Choices
  • Terms and Conditions
  • California Transparency Act
  • Legal Notices
  • Accessibility
  • Responsible Disclosure Statement
  • Surprise (Balance) Medical Billing Disclosure
  • Transparency in Coverage
  • Human Rights Policy
  • Vendor Code of Conduct
  • California Notice of Collection
  • Privacy Requests

© 2026, Tractor Supply Co. All Rights Reserved.