Spironolactone is a prescription diuretic used to treat congestive heart failure and fluid accumulation in the abdomen. Effective in horses, cats, and dogs, it is a potassium-sparing diuretic that reduces tissue fluid without causing potassium depletion and is also used to treat hypokalemia. Spironolactone is available by prescription only and is sold in individual tablets.How it Works

Spironolactone increases the volume of water excreted by the kidneys.

Special Precautions

• Do not administer spironolactone to pets who are allergic to it or have elevated levels of potassium, significant kidney disease, acute kidney failure, or Addison's disease.
• Do not administer to pets who might be used for breeding or pets who are not urinating.
• Use with caution in pets who are lactating or pregnant, or who have liver disease, uncontrolled diabetes, or other conditions causing imbalances of blood electrolytes.

Overdose Information

Immediately contact your closest animal hospital.

Side Effects

If your pet experiences any of the following adverse reactions, immediately discontinue spironolactone administration and seek emergency veterinary attention.

• Decreased urination
• Numbness
• Weakness
• Confusion
• Fatigue
• Shortness of breath
• Irregular heartbeat
• Allergic reaction (Hives, swelling of the face, tongue, or lips, or difficulty breathing)

If any of these less serious reactions occur, continue use and speak with your veterinarian.

• Dry mouth
• Decreased appetite
• Diarrhea
• Nausea
• Dizziness

Other reactions could occur. If your pet exhibits any reactions that seem bothersome or unusual, speak to your veterinarian.

Storage

Store at room temperature.