Prascend Tablets control the clinical signs associated with PPID in horses (formerly known as equine Cushing s disease).1 PRASCEND is a rectangular light red colored, half-scored tablet containing 1 mg pergolide, as pergolide mesylate, a dopamine receptor agonist for oral use in horses only. Within 3 months, you'll notice improved symptoms, as well as continued improvements throughout 6 months of use. Speak with your veterinarian today to see if these Prascend tablets for horses are suitable for your steed.How it Works

Pergolide mesylate is a synthetic ergot derivative and is a potent dopamine receptor agonist.

Special Precautions

Treatment with PRASCEND® (pergolide tablets) may cause inappetence. The use of PRASCEND in breeding, pregnant, or lactating horses has not been evaluated. The effects of pergolide mesylate on breeding, pregnant, or lactating horses are not known; however, the pharmacologic action of pergolide mesylate suggests that it may interfere with reproductive functions such as lactation. PRASCEND is approximately 90% associated with plasma proteins. Use caution if administering PRASCEND with other drugs that affect protein binding. Dopamine antagonists, such as neuroleptics (phenothiazines, domperidone) or metoclopramide, ordinarily should not be administered concurrently with PRASCEND (a dopamine agonist) since these agents may diminish the effectiveness of PRASCEND. Keep PRASCEND in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses. Adverse reactions may occur if animals other than horses ingest PRASCEND tablets. PRASCEND is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives. PRASCEND® (pergolide tablets) has not been evaluated in breeding, pregnant or lactating horses. Treatment with PRASCEND may cause loss of appetite. Most cases are mild. If severe, a temporary dose reduction may be necessary. PRASCEND tablets should not be crushed due to the potential for increased human exposure. Keep PRASCEND in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses. Adverse reactions may occur if animals other than horses ingest PRASCEND tablets. Refer to the package insert for complete product information.

Overdose Information

Contact your closest emergency pet hospital.

Side Effects

To read more about possible side effects, please review the package insert.

Storage

Store at or below 25°C (77°F).

Tips

Speak with your veterinarian to determine if Prascend® is a good option for your horse.