Lutalyse can be used to help control estrous timing, induce abortion, treat chronic endometriosis, synchronize estrus and more. It functions as a luteolytic agent for mares and cattle and can induce parturition in swine. Lutalyse is to be injected intramuscularly into the animal. FDA approved.How it Works

This product uses dinoprost tromethamine to:

• Control estrous timing in estrous cycling mares or in clinically anestrous mares with a corpeus luteum
• Induce parturition in swine
• Induce abortion in non-lactating or feedlot cattle
• Treat chronic endometriosis (pyometra) and silent (unobserved) estrus in cattle
• Synchronize estrus in cattle

Special Precautions

For a copy of the SDS (Safety Data Sheet), technical support, or to report a suspected adverse reaction, Zoetis, Inc. may be contacted at 1-888-963-8471. For more information about side effect reporting of animal drugs, contact the FDA by calling 1-888-FDA-VETS, or go to http://www.fda.gov/AnimalVeterinary/SafetyHealth. Refer to the packaging insert for all special precautions

Overdose Information

Immediately contact your closest emergency animal hospital.

Side Effects

Potential side effects include:

In mares:

• Decrease in rectal temperature
• Sweating

These effects are transient and are not detrimental.

• Other potential reactions include:
• Lying down
• Locomotor incoordination
• Abdominal discomfort
• Increased respiration rate
• Increased heart rate

These reactions typically occur within 15 minutes of injection and resolve within an hour. Even while experiencing a reaction, mares typically continue eating. In a study of several hundred mares on Lutalyse, a single anaphylactic reaction was reported, but was not substantiated.

In swine:

• Vomiting (at a dose of 100mg)
• Salivation
• Increased vocalization
• Dyspnea
• Hyperpnea
• Tail movements
• Abdominal muscle spasms
• Defecation
• Urination
• Itching
• Nesting behaviors
• Slight incoordination
• Pruritus
• Erythema

These reactions are typically short-term (10 minutes to 3 hours) and non-detrimental.

In cattle:

• Limited salivation

Storage

Store in a dry and cool environment. 68° to 77°F (20° to 25°C) 68° to 77°F