Comfortis Chewable Tablets for Dogs and Cats kills fleas and prevents and treats flea infestations for one month on cats and kittens 14 weeks of age or older and weighing 4.1 pounds or more. It also kills fleas and prevents and treats flea infestations for one month on dogs and puppies 14 weeks of age and older and weighing 5 pounds or greater.How it Works

The primary target of action of COMFORTIS in insects is an activation of nicotinic acetylcholine receptors (nAChRs).

Special Precautions

Not for human use. Keep this and all drugs out of the reach of children.

Overdose Information

In case of overdose, contact your closest emergency pet hospital.

Side Effects

FOR CATS: The most common adverse reaction recorded in clinical trials was vomiting. Other adverse reactions were: lethargy, decreased appetite, weight loss, and diarrhea. Use with caution with concomitant extra-label use of ivermectin. The safe use of Comfortis in breeding, pregnant, or lactating cats has not been evaluated. See Comfortis label for complete safety information. FOR DOGS: The most common adverse reaction reported is vomiting. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures. Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions. Use with caution in breeding females and dogs with pre-existing epilepsy. The safe use of Comfortis in breeding males has not been evaluated.

Storage

Store at room temperature between 68°-77°F.