ADVECTA Ultra Flea and Tick Protection for Large Dogs (21-55 lb.) contains the same active ingredients as K9 Advantix II for Dogs*. This formula kills and repels fleas, ticks, and mosquitoes, kills chewing lice, and prevents flea reinfestations for 30 days. *ADVECTA Ultra for Dogs is not manufactured or distributed by Bayer Healthcare LLC, the makers of K9 Advantix II. K9 Advantix II is a registered trademark of Bayer Healthcare LLC.READ ENTIRE LABEL FOR EACH USE It is a violation of Federal law to use this product in a manner inconsistent with its labeling. RESTRICTIONS: Do not allow children to apply product. Do not use on animals other than dogs. Do not use on puppies under 7 weeks of age or weighing less than 4 lb. Do not bathe or allow dog to swim for 24 hours after application. Do not get this product in dogs' eyes or mouth. Do not treat with more than one pesticide product at a time. Do not allow your dog to ingest this product. Do not apply more than one tube per treatment for one dog regardless of the dog's weight. Do not split tube between dogs and, use the entire contents of tube on each dog. Dog must be dry at time of application and remain dry for 24 hours after application. Do not have contact or allow children to have contact with the treated area until completely dry. Weigh your dog to be sure you are applying the right dose formulated for the weight of your dog. Separate treated dogs from one another and other animals to avoid chance of ingestion. Do not reapply for 30 days. How to Open: 1. Remove product tubes from the package. 2. Separate one tube from the others. Hold the tube with notched end pointing up and away from the face and body. Use scissors to cut off the narrow end at the notches along the line. How to Apply: 1. Invert tube over dog and use open end to part dog's hair. 2. Squeeze tube firmly to apply all of the solution to the dog's skin as a line starting from the back of the neck to a point midway between the neck and tail. FREQUENCY OF APPLICATION Advecta Ultra for Dogs kills fleas within 12 hours of application and lasts for 4 weeks. This product kills reinfesting fleas within 2 hours and prevents further infestations of fleas for 4 weeks. This product is waterproof and remains effective, even after bathing, swimming, or exposure to sunlight or rain. Monthly treatments are required for optimal control and prevention of fleas and ticks