Salix (Furosemide) Injectable is a diuretic used to promote the rapid elimination of abnormally retained extracellular fluid. It has a high degree of efficacy, low inherent toxicity, and a wide therapeutic index, making it an effective and safe treatment option. Salix is frequently used to treat cases of edema in cattle, horses, cats and dogs. It's sold in 50 mL vials to be injected directly into the animal.How it Works

The therapeutic effectiveness of Salix® comes from the action of the unaltered, intact molecule within the nephron, which inhibits sodium reabsorption in the ascending Henle loop and the distal and proximal tubule.

Special Precautions

• Use caution when administering to animals on potassium-depleting steroids.
• Excessive potassium loss in animals on glycosides or digitalis can cause digitalis toxicity.
• This medication is an incredibly effective diuretic. Like any diuretic, it can cause excessive diuresis if administered excessively. This can lead to dehydration, imbalance of electrolytes, and reduced plasma volume, which increases the risk of embolism, thrombosis, and circulatory collapse. Because of these concerns, animals should always be observed for early fluid depletion and electrolyte imbalance symptoms. If noted, corrective measures should be immediately initiated.
• Potassium deficiencies should be corrected with supplementation.
• Exercise caution when administering potassium tablets coated in enteric.

Overdose Information

Immediately contact your closest emergency animal hospital or vet.

Side Effects

Potential side effects include:

• Hearing loss (particularly common in cats in cases where large quantities were used in crisis management)
• Increased levels of blood sugar (not an issue in most animals; however, another diuretic might be better suited for patients with diabetes)
• Increased urination
• Increased thirst

Storage

Store in a dry and cool environment. Do not freeze

Tips

Excessive loss of potassium in patients receiving digitalis or its glycosides may precipitate digitalis toxicity. Caution should be exercised in animals administered potassium-depleting steroids. It is important to correct potassium deficiency with dietary supplementation. Caution should be exercised in prescribing enteric-coated potassium tablets.