Methotrexate is an immunosuppressive agent primarily used to treat lymphoma and other solid tumors in dogs and cats. Methotrexate is available in individual tablets.How it Works

Methotrexate works by slowing the growth of cells that multiply rapidly.

Special Precautions

Keep away from children and animals. When giving methotrexate to your pet, it is important to avoid human exposure as much as possible. Wear gloves and immediately wash your hands after handling the drug. If you need to split the tablet or handle a broken tablet, wearing gloves is extremely important. Because of the nature of the drug and its toxicities, pregnant or nursing animals should avoid using methotrexate. Methotrexate can interact with several medications. Some of these include NSAIDS, cyclosporine, and folic acid. It is important to discuss with your pet's veterinarian all medications, supplements, and herbal products you may be giving to your pet before starting methotrexate. The veterinarian may also monitor your pet for toxicities associated with methotrexate by watching for signs of irritation of the gastrointestinal tract. They may also perform lab tests such as a complete blood count, renal function tests, and liver function tests. It is important to give your pet this medication exactly as prescribed and to not discontinue the drug without consulting with your pet's veterinarian. If you miss giving your pet the dose, give it to him as soon as you remember. If it is close to the next dose, skip the missed dose and continue on your normal schedule. If you are unsure about when to give a missed dose, contact your pet's veterinarian.

Overdose Information

Immediately contact your closest emergency animal hospital or vet.

Side Effects

Diarrhea, Nausea, Lack of an appetite (especially in cats), Vomiting (especially in dogs), Hair loss, Lack of energy.

Storage

Store in a cool/dry place away from animals and children.