Equioxx (Firocoxib) Oral Anti-Inflammatory Paste is formulated to help treat osteoarthritis symptoms in horses. With just a single dose, horses can enjoy pain relief, decreased inflammation and improved mobility for up to 24 hours. Available in a 6.93g tube of paste and has a palatable flavor. Also available in a chewable tablet form (sold separately).How it Works

EQUIOXX® (firocoxib) is a coxib class NSAID that targets COX-2 (cyclooxygenase-2), which is part of the chemical pathway resulting in pain and inflammation, while sparing COX-1 (cyclooxygenase-1), which help maintain normal bodily functions like blood flow to the kidneys and gastric mucosal protection.*1-4 *Clinical relevance has not been established. 1. Kvaternik V, Pollmeier M, et al, Pharmokinetics and metabolism of orally administered firocoxib, a novel second generation coxib in horses. J Vet Pharmacol Ther. 2007;30(3):208-217. 2. Data on file at Boehringer Ingelheim. Clinical Experience Report PHN 471, PR&D 0030701 3. Data on file at Boehringer Ingelheim, "Clinical Experience Report, PHN 471, Target Animal Safety Evaluation, Firocoxib (ML-1,785,713) Oral Paste for Horses." 4. Warner TD, Mitchell JA. Cyclooxygenase-3 (COX-3): filling in the gaps toward a COX continuum. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13371-3.Insert #4

Special Precautions

• Do not administer to horses with NSAID or firocoxib hypersensitivity.
• Only for oral administration to horses.
• Not for use in horses intended for food slaughter.
• Do not use in humans.
• Keep away from children.
• If accidentally ingested by a human, seek medical advice.
• Drug toxicity symptoms should be well-understood and monitored.
• A complete history and physical exam are recommended before initiating treatment with this or any NSAID, and periodic re-examination may be recommended by your veterinarian.

Overdose Information

Immediately contact your closest emergency animal hospital or vet.

Side Effects

The most common side effects reported with EQUIOXX® (firocoxib) therapy involve erosions and ulcers on the tongue, lips and skin of the mouth and face as well as on the kidney. GI, kidney and liver problems have also been reported with other NSAIDs.

Storage

EQUIOXX® (firocoxib) Oral Paste: Store below 86°F (30°C) with brief excursions up to 104°F (40°C) permitted.