Clomicalm (Clomipramine HCl) Tablets are indicated for the treatment of separation anxiety and associated behaviors in dogs. By increasing serotonin levels in the brain, Clomicalm helps reduce symptoms such as drooling, destructive behavior, and excessive barking when used in conjunction with a behavioral management plan. These tablets are intended for dogs 6 months of age and older.How it Works

Clomicalm is a tricyclic antidepressant. It alters the levels of specific brain chemicals, especially serotonin. Serotonin is associated with positive emotions. After a neuron releases serotonin, it is collected by an uptake receptor and recycled. The clomipramine hydrochloride in Clomicalm binds to that receptor and prevents the removal of excess serotonin, increasing the positive neural signal in the brain.

Special Precautions

Clomicalm:

• Should not be used alongside Anipryl (selegiline) tablets or Preventic collar
• Should only be administered with veterinarian approval
• Should not be administered to breeding dogs

Clomicalm should be carefully and thoughtfully administered to dogs with:

• Epilepsy
• Cardiovascular dysfunction
• Urinary retention
• Reduced gastrointestinal motility
• Narrow angle glaucoma

Overdose Information

In case of overdose, contact your closest emergency pet hospital.

Side Effects

While Clomicalm is generally well-tolerated, the following side effects may occur:

• Elevated liver enzymes
• Depression
• Vomiting
• Lethargy
• Increased thirst
• Diarrhea

Storage

Store dry at room temperature 59°- 86° F (15-30° C). Unused tablets should be stored in original container.

Tips

While administering Clomicalm with food is not a necessity and the medication will still work effectively without doing so, food could reduce the likelihood of vomiting.