Zoetis Apoquel

When dogs suffer from allergies, every scratch, lick and bite in search of relief does more harm than good. Apoquel (oclacitinib tablet) from Zoetis is a trusted prescription treatment that may help. It is formulated to provide rapid relief from the itching and inflammation associated with allergic and atopic dermatitis in dogs. With targeted relief and proven efficacy, Apoquel can help your four-legged companion feel more comfortable while supporting long-term allergy management, and it is available at Tractor Supply.

Apoquel Overview

As a leading animal health company, Zoetis is dedicated to developing innovative solutions that help pets live healthier, happier, more comfortable lives. With decades of expertise in veterinary medicine, Zoetis invests in research, development and clinical science to better address the most common health challenges pet owners and their animals face.

Apoquel is one of the most widely recognized products in the Zoetis companion animal portfolio, reflecting the company's commitment to advancing veterinary medicine. Acknowledging the need for targeted treatment, Zoetis developed Apoquel to address the underlying pathways involved in allergic itch. Unlike broad immunosuppressive therapies, Apoquel is a Janus kinase (JAK) inhibitor, meaning it works by disrupting the signals in the body that cause itching and inflammation. This targeted mechanism provides effective symptom relief, while supporting a more personalized approach to allergy management.

Since its introduction, Apoquel has become a foundational therapy for canine allergic skin disease, helping countless dogs achieve relief from chronic itching and inflammation. The brand's rapid onset of action and established clinical performance have made it a trusted option for both short-term symptom control and long-term management. Through ongoing advancements in research, clinical studies and veterinary education, Zoetis continues to further the field of animal health, providing products that help pets thrive while enjoying Life Out Here, including Apoquel.

About Our Apoquel Selection

We are a convenient destination for pet owners seeking trusted veterinary health products, such as Zoetis Apoquel. As a go-to for pet care essentials, we provide access to canine prescription medications that help support your best friend's comfort, health and quality of life. Whether managing seasonal allergies, environmental sensitivities or chronic conditions, we offer Apoquel solutions, all backed by the science and innovation of Zoetis.

Canine Skin and Allergy Treatments

Allergies in canines can cause persistent itching, licking, chewing and discomfort, which is why we offer Apoquel dog skin and allergy treatments. These solutions are designed to address allergy-related symptoms and support long-term skin health with a targeted approach, providing fast relief while reducing irritation.

The right treatment aims to deliver several important benefits for dogs experiencing allergic skin conditions. Effective management helps minimize scratching and chewing behaviors that may lead to skin damage or secondary bacterial infections. Relief from symptoms also helps improve comfort, support coat condition and contribute to a happier pup.

Veterinary Prescription Required

Pet owners play an important role in comprehensive allergy management and ongoing canine wellness. Because Apoquel is a prescription medication, it should be used only under the guidance of a licensed veterinarian. Your vet will help you determine if Apoquel is the best treatment based on your pet's age, medical history, allergy symptoms and overall health status.

Support Canine Allergy Management with Zoetis Apoquel from Tractor Supply

When it comes to managing canine allergies, the right treatment makes all the difference in your pet's comfort. Zoetis Apoquel is a trusted prescription option for relieving allergic itch and supporting healthier skin. Help your dog stay active and happy year-round with our selection of Apoquel, offered online or at your local Tractor Supply store.

<sub>IMPORTANT SAFETY INFORMATION
Apoquel & Apoquel Chewable
Do not use Apoquel or Apoquel Chewable in dogs less than 12 months of age or those with serious infections. Apoquel and Apoquel Chewable may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post approval. Apoquel and Apoquel Chewable have not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel and Apoquel Chewable have been used safely with many common medications including parasiticides, antibiotics and vaccines. See full Prescribing Information at ApoquelTabletAndChewablePI.com.

INDICATIONS: Control of pruritus (itching) associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.

*Based on a model study for flea allergic dermatitis.

†No specific studies have been conducted to compare the PK of Apoquel Chewable when administered with or without food. The active ingredient in Apoquel Chewable has been shown to be unaffected by food.

References
1. Data on file, Apoquel/Cytopoint Vet Tracker Wave 18, 2024, Zoetis Inc.
2. Kynetec - PetTrak, US Pruritus Factored National. Dec. 2023 MAT Canine Pruritus, Total Unique Patients on Apoquel. Zoetis Inc.
3. Gonzales AJ, Bowman JW, Fici GJ, et al. Oclacitinib (APOQUEL(®) is a novel Janus kinase inhibitor with activity against cytokines involved in allergy. Journal of Veterinary Pharmacology and Therapeutics. 2014;37(4):317-324. doi:10.1111/vp.12101.
4. Gadeyne C, Little P, King VL, Edwards N, Davis K, Stegemann MR. Efficacy of oclacitinib (Apoquel®) compared with prednisolone for the control of pruritus and clinical signs associated with allergic dermatitis in client-owned dogs in Australia. Vet Dermatol. 2014;25(6):512-518,e86. doi:10.1111/vde.12166.
5. Data on file, Study Report A161C-US-21-C02, 2022, Zoetis Inc.
6. Cosgrove SB, Wren JA, Cleaver DM, et al. Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis. Vet Dermatol. 2013;24(5):479- e114. doi: 10.1111/vde.12047.
7. Cosgrove SB, Cleaver DM, King VL, et al. Long-term compassionate use of oclacitinib in dogs with atopic and allergic skin disease: safety, efficacy and quality of life. Vet Dermatol. 2015;26(3):171-179, e35. doi: 10.1111/vde.12194.
8. Data on file, A Ten-Year Post-Approval Safety Review for Apoquel in the US (May 2013 to May 2023), Zoetis Inc.
9. ZMR: Kynetec GAH- 284 Cytopoint & Apoquel Pets Since Launch, January 2014 to December 2025</sub>