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4.6 out of 5 stars. 401 reviews
Home / Pet / Dog / Dog Flea & Tick / Dog Topical Spot-on Flea & Tick Control / Frontline Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.

Frontline Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.

4.6401 Reviews

Item # 2427216

Frontline Plus Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.

4.6401 Reviews

Item # 2427216

Image showing  Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.
Image showing  Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.
Image showing  Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.
Image showing  Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.
Image showing  Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.
Image showing  Flea and Tick Topical Treatment for Dogs 89-132 lb., 3 ct.
Highlights
  • Breed Size:Extra Large
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$45.99

Pet Breed Size: 89 to 132 lb.

Months Supply: 3 Months


Buy In Store: at Grassland (franklin) TN

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4 In Stock in Aisle 5

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Protect your dog with FRONTLINE - the #1 name in flea and tick protection.* FRONTLINE Plus for Dogs provides fast-acting, long-lasting, flea and tick protection proven to kill adult fleas, flea eggs, flea larvae, chewing lice, and ticks. Trusted by pet owners for over 20 years,** one easy flea and tick topical application treatment works for 30 days.

  • Keep your dog protected from fleas & ticks all month long with FRONTLINE, the #1 name in flea and tick protection. FRONTLINE Plus for Dogs is a fast-acting, long-lasting flea & tick topical treatment thats proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease.
  • Break the flea life cycle with FRONTLINE Plus. Specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs, and flea larvae and prevent new infestations.
  • Trusted by pet owners for over 20 years, ** FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days.
  • FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5 lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products.
  • Treat the dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
  • Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus.

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Reviews

Rating Snapshot

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320 reviews with 5 stars.
39 reviews with 4 stars.
20 reviews with 3 stars.
5 reviews with 2 stars.
17 reviews with 1 star.

Overall Rating

4.6
321 out of 338 (95%) reviewers recommend this product

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Summary of Reviews
AI-generated using English reviews only
The Frontline flea and tick prevention product is a long-standing and widely used option for many pet owners. Most reviewers report the product effectively protects their dogs and cats, with some noti...
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Helpful?

Most Helpful Favorable Review

5 out of 5 stars.

Frontline Plus

15 years ago
Only but this product at Tractor Supply. Know I can buy products from them and they will work. We had a severe tick problem in our back yard due to a field behind our property and this has worked like a charm. Have not seen one tick or flea on our dog since we started using the product. Will continue to buy this product and shop at Tractor Supply where they care about thier customers.
6 people found this helpful
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Most Helpful Critical Review

1 out of 5 stars.

Used in past but.....

11 years ago
My dog still had ticks and fleas, did nothing to control nor kill them. I went back to store and complained and was told that K-9 Advantage is much better than Frontline so I purchased K-9 Advantage and it took care of the problems. Everyone has their own preference for tick and flea control but after using K-9, I will never purchase anything but that. Not one that likes wasting my money and most important, have my dog suffer when I did apply a tick and flea control that did not work. K-9 Advantage, try it, you will see a difference.
5 people found this helpful
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Customer Images and Videos

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Our babies
Abby, Pixie, & Jazz
Our dog, Schnitzel Annie
My baby
1 out of 5 stars.

What’s changed with Frontline Plus??

13 days ago
I am so disappointed! I’ve used frontline plus for years. Just purchased 6/28/25. Bathed my dog extremely well, dried him and waited an additional hour to make sure he was dry just in case this affected how it worked. I applied as directed and as I have for years! Next day still has live fleas. It’s now 7/2/25 and he still has many live fleas! Has done nothing! I will be returning remaining 2 doses for an exchange of another brand in hopes my dog gets some relief! Highly disappointed in this brand!

No, I do not recommend this product.

PA
1 out of 5 stars.

WASTE

7 months ago
They should stop selling this product as it is no longer effective and is a complete waste of money .
SweepstakesYes

No, I do not recommend this product.

Dublin, GA
5 out of 5 stars.

Helpful and affordable

a year ago
Works well, easy to apply, didn't irritate my dogs skin
SweepstakesYes

Yes, I recommend this product.

Bellville, Ohio
3 out of 5 stars.

Good enough

a year ago
It works in a pinch, but there are better products.

Yes, I recommend this product.