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4.8 out of 5 stars. 95 reviews
A woman outside with a dog
A woman outside with a dog

Frontline Plus Topical Flea, Tick and Lice Treatment for Cats

Frontline Plus Topical Flea, Tick and Lice Treatment for Cats

Item # 2427193

Frontline Plus Frontline Plus Topical Flea, Tick and Lice Treatment for Cats
Frontline Plus Frontline Plus Topical Flea, Tick and Lice Treatment for Cats

Save up to 40% on first Smart Supply

or up to 20% on one‑time purchase

Smart SupplyTM

Auto order & save every day

$45.99

Save 40% on your first Smart Supply order, up to $25.

Save 5%Save 5% on Smart Supply future orders.
ConvenientConvenient deliveries on a schedule you choose
FreeFree Standard Delivery on Rx orders over $30 & non-Rx orders over $49
No commitmentNo commitment easily cancel anytime

One Time Purchase

$45.99

Pet Breed Size: 1.5 lb. and over

Months Supply: 3 Months


Notice:
This item is non-returnable.
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Frontline Plus Topical Flea, Tick and Lice Treatment for Cats

Item # 2427193

Frontline Plus Frontline Plus Topical Flea, Tick and Lice Treatment for Cats
Frontline Plus Frontline Plus Topical Flea, Tick and Lice Treatment for Cats

Save up to 40% on first Smart Supply

or up to 20% on one‑time purchase

Smart SupplyTM

Auto order & save every day

$45.99

Save 40% on your first Smart Supply order, up to $25.

Save 5%Save 5% on Smart Supply future orders.
ConvenientConvenient deliveries on a schedule you choose
FreeFree Standard Delivery on Rx orders over $30 & non-Rx orders over $49
No commitmentNo commitment easily cancel anytime

One Time Purchase

$45.99

Pet Breed Size: 1.5 lb. and over

Months Supply: 3 Months


Delivery to

Pickup Nearby at FRANKLIN TN(6.7) miles Free

Pickup Later at Grassland (franklin) TN


Notice:
This item is non-returnable.
Neighbor's Club logo
Neighbor’s Club Members earn points with purchases.

Sign in or Join Now

For pets needing protection during flea and tick season, rely on the Frontline Plus Topical Flea, Tick and Lice Treatment for Cats to help keep them safe. With 2 active ingredients, including (S)-methoprene and fipronil, this cat flea and tick prevention works to not only kill adult ticks and fleas, but also flea larvae, eggs and chewing lice, helping to protect against reinfestation. One dose of this flea and tick prevention for cats will keep pets safe for up to 1 month. Reapply monthly for year-round protection.How it Works

FRONTLINE® Plus for Cats contains fipronil and the insect growth regulator (IGR) (S)-methoprene. Fipronil kills fleas by affecting their nervous system, making them hyperactive before dying. These dying fleas often rise to the top of the cat's hair coat as they are dying. The (S)-methoprene prevents all flea stages (eggs, larvae, pupae) from developing.

Special Precautions

For external use only. Do not use on kittens under 8 weeks of age or 1.5 lbs. Individual sensitivities, while rare, may occur after using any pesticide product.

Overdose Information

Contact your closest emergency pet hospital.

Side Effects

Cats may experience some temporary irritation at the site of application. If signs persist or become more severe within a few days of application, consult a veterinarian immediately.

Storage

Store unused product in original container only, out of reach of children and animals.

Looking for more information on flea and tick control? Check out our flea and tick control buying guide in the product documents section.

  • Available in 3-, 6-, 8- and 12-month treatments of flea and tick prevention for cats
  • Fast-acting and long-lasting treatment kills adult fleas, larvae and eggs, as well as chewing lice and ticks that may transmit Lyme disease
  • Waterproof and easy-to-apply formula won't wash off after applying
  • 2 active ingredients, including (S)-methoprene and fipronil, protects against fleas and ticks for up to 1 month with just 1 dose
  • Formulated for kittens and cats ages 8 weeks and older and weighing 1.5 lb. and more
  • Works to break the life cycle of fleas, killing adult fleas, eggs and larvae to prevent future infestations
  • Must reapply monthly for year-round protection
  • Trusted by pet owners for more than 20 years

Frequently Bought Together

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Reviews

Rating Snapshot

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79 reviews with 5 stars.
13 reviews with 4 stars.
2 reviews with 3 stars.
1 review with 2 stars.
0 reviews with 1 star.

Overall Rating

4.8
87 out of 88 (99%) reviewers recommend this product

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Summary of Reviews

AI-generated from customer ratings & reviews, and may include incentivized reviews.
Customers overwhelmingly praise this flea and tick control solution as highly effective and reliable, with most reporting complete eradication and years of continuous use—many citing 10 to 15 years without recurrence. The topical treatment is consistently described as easy to apply, with cats tolera...
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This summary is AI-generated from ratings and reviews across multiple languages.
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1 to 4 of 95 Reviews .
1 – 4 of 95 Reviews
Review 1

It works.

11 days ago
It works! We will reorder.

Yes, I recommend this product.

SWAN LAKE OK
Review 1

NOT WORTH THE MONEY DONT WORK

3 months ago
I PAID ALOT OF MONEY FOR THIS AND IT DONT WORK WELL AT ALL AM VERY UPSET. I BATH MY CATS FIRST THEN TOOK THE FLEA COMB THEN AND THEN PUT THIS ON THEM. WELL AFTER A WEEK THEY STILL HAVE FLEAS. DAWN SOAP KILLS BETTER THEN THIS ITS SAD ALL THE MONEY WASTED
SweepstakesYes

No, I do not recommend this product.

Reviews 9

Works for my 3 cats

a year ago
Works for my indoor/outdoor cats.
SweepstakesYes

Yes, I recommend this product.

Ga.
Review 1

Great quality

a year ago
Best deals for the price

Yes, I recommend this product.