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[Home](https://www.tractorsupply.com/tsc/cms/life-out-here) 2. [The Barn](https://www.tractorsupply.com/tsc/cms/life-out-here/the-barn) 3. [Livestock](https://www.tractorsupply.com/tsc/cms/life-out-here/the-barn/livestock) 4. Cattle Medication # Cattle Medication May 18, 2023 [Updated by Katie Navarra](https://www.tractorsupply.com/tsc/cms/life-out-here/authors/katie-navarra-equine-livestock-author)  Vaccinations and medications are critical to maintaining herd health and productivity.  How they are stored and administered influences their efficacy and safety. ## __Veterinary Client Patient Relationship__ Establishing a relationship with a veterinarian, often referred to as a veterinarian-client-patient-relationship (VCPR), is the first step when deciding what to give an animal based on its current health status, farm management practices, and disease risk. Having a VCPR does not necessarily mean a veterinarian needs to visit the farm for every vaccination or treatment. Once they are familiar with your herd, they can develop an animal health program that meets your specific needs. Most importantly, if you don’t have a VCPR established, you will be unable to get a number of antibiotics that you may be currently using to treat animals. ## __Antibiotic changes on the horizon__ According to Dr. Craig Payne, extension veterinarian at the University of Missouri several antibiotics approved for use in animals will transition from over-the-counter availability (OTC) to requiring a veterinary prescription later in 2023.  Payne describes this action as the final phase of FDA’s efforts to bring all medically important antibiotics approved for animal use under veterinary oversight.  “The first phase occurred on Jan. 1, 2017, when medically important antibiotics approved for use in animal feed transitioned from OTC availability to requiring a Veterinary Feed Directive (VFD) and medically important antibiotics approved for use in drinking water transitioned from OTC availability to requiring a prescription,” Payne said. Those changes affected many of the antibiotics used in animal health, but a few remained available OTC.  However, on June 11, 2021, FDA released Guidance for Industry (GFI) #263 which outlined the process for transitioning these remaining OTC antibiotics to prescription status with the expectation this would go into effect two years later. “As a result, any antibiotics affected by #263 that are entering distribution channels after June 11, 2023, are expected to display the following language on the label: Caution: Federal law requires the use of this drug by or on the order of a licensed veterinarian”, Payne said.  “Once antibiotics with this revised label appear at retail locations, a veterinary prescription will be required when they are sold or dispensed, regardless of the species of animal they will be used in or what disease you intend treat.”    Below are a few examples of the commonly used antibiotics that will transition from OTC availability to requiring a veterinary prescription.  __Cephapirin, Cephapirin Benzathine__ Product examples: *Intramammary tubes:* ToDAY® and ToMORROW® __Lincomycin__ Product examples: *Injectables:* Lincomix® 100, Lincomix® 300, LincoMed™ 100, LincoMed® 300 __Oxytertracycline__ Product examples*: Injectables:* Liquamycin® LA-200®, Noromycin® 300 LA, Bio-Mycin® 200, Agrimycin 200, etc. *Boluses:* Terramycin® Scours Tablets, OXY 500 Calf Boluses __Penicillin G Procaine, Penicillin G Benzathine__ Product examples: *Injectables:* Penicillin Injectable, Dura-Pen, Pro-Pen-G®, Combi-Pen 48®, etc. *Intramammary tubes*: Masti-Clear®, Go-dry™, Albadry Plus®  __Sulfadimethoxine, Sulfamethazine__ Product examples: *Injectables:* Di-Methox 40%, SulfMed™ 40% *Boluses:* Albon®, Sustain III® Cattle & Calf Boluses, Supra Sulfa III Cattle & Calf Boluses __Tylosin__ Product examples: *Injectables:* Tylan™ 50, Tylan™ 200 ## Vaccines for cattle Vaccines will remain available over the counter and provides critical protection against common cattle diseases. A veterinarian can provide guidance on which vaccines to give and when.  __Alpha-7__ Approved uses: For clostridial or blackleg (must be boostered). __Bar Vac CD-T (Fermicon)__ Prevents enterotoxemia (overeating disease) and tetanus. __C & D Antitoxin__ To immunize healthy yet susceptible animals against enterotoxemia (overeating disease) and tetanus caused by the toxins of clostridium perfringens types C and D and clostridium tetani. __Lepto 5__ For immunization against five strains of leptospira. __Sulfadimethoxine, Sulfamethazine__ For healthy cattle to aid in control and prevention of pinkeye caused by Moraxella bovis. __Piliguard Pinkeye (Moraxella bovis Bacterin)__ For healthy cattle to aid in control and prevention of pinkeye caused by Moraxella bovis. __Respishield 4 (Triangle 4 + Type IIBVD)__ For vaccination of healthy cattle against BRSV, IBR, BVD and PI-3. Bovine rhinotracheitis-virus diarrhea-parainfluenza-3-respiratory syncytial virus vaccine. Killed virus. Recommended for all stages of pregnancy, all ages beef or dairy cattle, all situations where you can't afford the stress of an MLV vaccine. __Respishield 4L5 (Triangle 9 + Type IIBVD)__ Vaccinates against BRSV, IBR, BVD, PI-3 and 5-Way Lepto. __Respishield 4 (Triangle 4 + HS)__ For vaccination of healthy cattle to protect against infectious bovine rhinotrachetis (IBR), bovine virus diarrhea (BVD), parainfluenza-3 (PI3), bovine respiratory syncytial virus (BRSV) and infections caused by Haemophilus somnus. __Ultrabac 7__ For use in healthy cattle for the prevention of blackleg (CI, chauvoel), malignant edema (CI, septicum), black disease (CI. novyl), and Clostridium sordel and Clostridium perfringens types C and D enterotoxemia. ## Proper livestock medication handling Animal health products are only effective when kept and administered according to the label instructions. All labels include storage instructions and expiration dates. “The expiration date is contingent upon storage conditions. If it is not being maintained according to manufacturer's instructions, who is to say that the expiration date still applies,” Payne said. “Pay attention to products you’re pulling out of inventory to use. If they are expired, they may no longer be efficacious or safe to use so consider discarding it.  You can also contact the manufacturer if you have additional questions.” In addition to proper storage, how vaccines are handled and administered in the field influences their efficacy. Payne encourages producers to visit with their veterinarian or reference the [Beef Quality Assurance](https://extension.okstate.edu/fact-sheets/feed-additives-for-beef-cattle-production.html "Links to external site for the Beef Quality Assurance Program.") Program  or the [National Dairy FARM](https://nationaldairyfarm.com/ "Links to external site for the National Dairy Farmer's Association.") (Farmers Assuring Responsible Management) for specifics on vaccine handling and administration. * * * Get the top deals, latest trends and more Sign up for emails from Tractor Supply today. 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